This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). Wang L, Fan JP, Xu Y, Wang JL, Wang MZ. One study of over 3,000 people who got a COVID-19 vaccine did not find any increased side effects or other issues among people with different blood types. The log-transformed level of interferon-gamma, CD4+ T-cell count, B-lymphocyte count, and IL-6 level were used as independent variables. The site is secure. INTRODUCTION The goal of this study was to evaluate the side effects of application of the Pfizer BioNTech vaccine on the workers at a Mexican hospital. In the future, we will include more participants after administering booster vaccines and conduct pseudo-virus neutralization tests to address these limitations. 20052022 MedPage Today, LLC, a Ziff Davis company. The severity of the COVID-19 disease Recent data suggests that people with blood type A have a significantly higher risk of acquiring COVID-19 than non-A blood types. So it follows that the response may be most intense around the source of the intruder: a needle in the arm. Accessibility Participants with an interval of <40 days between the doses of vaccination had lower levels of neutralizing antibodies than those with an interval of >40 days between the doses (B = 0.015 (0.010.021), 95% CI 0.010.021; p < 0.001) (Figure2E; Table2, and Table S3). doi:10.1093/nsr/nwab193, 14. Read on to find out if you're safe, and for more risky behavior to be aware of, know that It Only Takes This Long to Get COVID in a Room With Someone Who Has It. We also evaluated CD4+ T-lymphocyte counts, B-cell counts, and IFN- and IL-6 levels after stimulation with the S protein of SARS-CoV-2 in 543, 539, 513, and 512 individuals, respectively. Figure2 Quantitation of antibodies on days 1240 following administration of the Chinese inactivated vaccine. One, for instance, suggests that people with Type A may have a higher risk of catching Covid-19 and of. The full eligibility criteria were provided in the volunteer recruitment notification distributed through social networks, including WeChat groups. On the other hand, the frequency of blood group O was significantly lower in the COVID-19 patients, compared to the control group . But both docs agree it shouldnt actually change anyones behavior. In all cases, the immune system creates antibodies that activate platelets in the bloodstream, he said. But the virus is still in your system and you can still pass it to someone else.". In fact, the findings suggest that people with blood type A face a 50 percent greater risk of needing oxygen support or a ventilator should they become infected with the novel coronavirus. The profile of solicited adverse events in this study was consistent with that of a previous study (20). xhr.setRequestHeader('Content-Type', 'text/plain;charset=UTF-8'); Online ahead of print. Table5 Factors associated with B-lymphocyte count after the administration of the inactivated Chinese COVID-19 vaccine. But let's back up first. It may affect your immune systems strength or your inflammatory response to the infection. Front Public Health. The study complied with the principles of the Declaration of Helsinki and Good Clinical Practice, and was approved by the Ethics Committee of Henan Provincial Peoples Hospital (approval number 20210051, date of approval May 24, 2021). Lower antibody concentrations were correlated with older age, longer duration after vaccination, non-health care workers, mixed-manufacturer vaccinations, and intervals of less than 40 days between two doses of vaccination, whereas lower IFN- levels and B-lymphocyte counts were associated with older age, blood type A, and non-health care workers. In the case of the two mRNA COVID-19 vaccines, well over 90% of . One study published by the CDC reports that from March 2020 to January 2021, patients with COVID-19 had nearly 16 times the risk for myocarditis compared with patients who did not have COVID-19. A new study has good news for more than a third of Americans. You'll always want to stay at your vaccination site for at least 15 minutes after you get the shot (30 minutes if you've had a severe allergic reaction before). Received: 25 November 2022; Accepted: 20 February 2023;Published: 03 March 2023. If You Have One of These Blood Types, You May Be Safe From COVID, It Only Takes This Long to Get COVID in a Room With Someone Who Has It, These 2 Places Could Be Closing Soon, White House Official Warns, How Likely You Are to Catch COVID in the Next Month, Expert Says, If You Have This Symptom, There's an 80 Percent Chance You Have COVID, tracked the blood types of nearly 2,200 COVID-19 patients, A blood types were significantly more likely. O is the most common blood type in the U.S.: 37 percent of white Americans fall into this category, according to the American Red Cross, with the numbers rising to 47 percent among African-Americans, 53 percent among Latinx-Americans, and 39 percent of Asian-Americans. Common side effects included: tenderness at the injection site for 73% of participants pain upon and after vaccination for 60% of participants fatigue for 50% of the participants muscle pain. Typical side effects include pain at the injection site, fever, fatigue, headache, muscle pain, chills and diarrhoea. 2021;76:e3286. *Correspondence: Yi Li, liyilebmed@henu.edu.cn, These authors have contributed equally to this work, Advancing the Understanding of Emergence of SARS-CoV-2 Genetic Variants and COVID-19 Vaccine Efficacy: Essential Clinical and Molecular Insights and Breakthroughs, View all var xhr = new XMLHttpRequest(); National Library of Medicine Use or keep moving your arm. Opens in a new tab or window, Share on Twitter. The following outcomes were selected and defined by the authors based on information from regulatory authorities, previous studies, large-scale adverse events initiatives: febrile seizure, aseptic. People with blood type O may be less vulnerable to Covid-19 and have a reduced likelihood of getting severely ill, according to two studies published Wednesday. It is observed that severity of infection would be high among B blood group people. Neurological side effects occur with any of the approved vaccines but VST particularly occurs after vaccination with vector-based vaccines. Follow-up visits were scheduled on days 130 to measure vital signs, review any solicited and unsolicited adverse events, and update medical and medication records. Possible side effects: Pain, redness, or swelling at the site where the shot was administered, and/or tiredness, headache, muscle pain, chills, fever, or nausea throughout the rest of the body. 2021;2(9):709056. doi:10.3389/fpubh.2021.709056 Front Neurol. Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine in children aged 6-17 years: A preliminary report of COV006, a phase 2 single-blind, randomised, controlled trial. Applies to sars-cov-2 (covid-19) mrna-1273 vaccine: intramuscular suspension. These include soreness where the jab was. Natl Sci Rev (2021) 8:nwab193. . This narrative review was conducted to collect and discuss published data about neurological side effects of SARS-CoV-2 vaccines in order to discover type, frequency, treatment, and outcome of these side effects. -, Wang MW, Wen W, Wang N, et al. Epub 2023 Jan 9. Less than 2% of the population have B negative blood. This finding suggests that cellular immune responses lasted longer than humoral responses in the vaccinated population. Bethesda, MD 20894, Web Policies Clinics (Sao Paulo). Opens in a new tab or window, Visit us on LinkedIn. (19, 20), we divided participants into three BMI groups: <18.5, 18.523.9, and >23.9 kg/cm2. Si vous ne souhaitez pas que nos partenaires et nousmmes utilisions des cookies et vos donnes personnelles pour ces motifs supplmentaires, cliquez sur Refuser tout. But theres another interesting layer to a potential protective element in Type O blood: something called von Willebrand factor, which is a glycoprotein in charge of repairing damage to blood vessels by prompting your blood to clot. At intervals of 2 months, 8 mL of blood samples was collected from volunteers and distributed into four tubes (2 mL/tube) with or without the EDTA anticoagulant (two tubes for each) to detect neutralizing antibodies and cellular immune response parameters. The participants in the study (mixed-manufacturer vaccination for the two doses) and control (same-manufacturer vaccination for both doses) groups remained in local community health centers for at least 30min after vaccination to monitor safety, and the occurrence of any adverse event during this observation period was recorded. Researchers have been talking about blood type and COVID-19 susceptibility for months. Clipboard, Search History, and several other advanced features are temporarily unavailable. doi:10.6061/clinics/2021/e3286 (EG) Kinetics of interferon (IL)-6 levels according to (E) age, (F) vaccine manufacturer, (G) occupation and (H) interval between doses of vaccination. Here is all the latest news about convicted killer, Alex Murdaugh. They noted conflicting research about blood types and COVID, with studies around the world finding links between the two -- particularly, increased susceptibility in people with type A and/or decreased risk with type O -- while others found no links. First there is a reaction in the arm where you are injected - think swelling and soreness - as the immune system swings into gear. J Med Internet Res (2021) 23:e26089. But VWF also encourages clotting. A linear regression analysis using a mixed-effect model showed that age, vaccination mode, occupation, interval between doses of vaccination, and vaccination duration were factors significantly associated with the levels of neutralizing antibodies (Tables13; Tables S1S7). Associations were observed between blood type and production of neutralizing antibodies and IFN-. Blood type is actually a pretty weak player, Dr. Udden says. The couple will likely attend the big event. ae0fcc31ae342fd3a1346ebb1f342fcb, "An Rh status seemed protective against SARS-CoV-2 infection," the study authors wrote. "Our next study will specifically look at such antibodies, and whether they explain the protective effect," Ray told Reuters. Furthermore, based on the study of Lusting etal. The observations made in the "Study of blood group analysis and its correlation with lymphopenia in Covid- 19 infected people" were carried during the first wave of cases for two months in a retrospective manner. April 5, 2021. Not everyone gets side effects. ABO blood typing was performed using a test-tube method according to the manufacturers protocol (Chengdu Xiehe Ltd., Co., Chengdu, China). The number of participants was relatively small, and at the time of the clinical study design, the administrators did not advocate the administration of vaccines from different manufacturers for separate doses. This work was supported by the Henan Provincial Key Programs in Science and Technology [grant numbers 202102310355 and 182102311241] to YY and WY, and the Joint Program of Medical Science and Technology Research of Henan Province [grant numbers SB 201903018, LHGJ 20190611, and LHGJ 20200016] to YY and BW. The https:// ensures that you are connecting to the 2021 Sep 2;17(9):2957-2958. doi: 10.1080/21645515.2021.1922061. Other neurological side effects occur in a much lower frequency. Reported side effects of COVID-19 vaccines have mostly been mild to moderate and have lasted no longer thana few days. Except for blood type, all demographic and baseline characteristics were balanced between the intervention and control groups (Table1). Patients with type O and rhesus negative (Rh-) blood groups may have a lower risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and severe coronavirus disease 2019 (COVID-19) illness, according to a study published in the Annals of Internal Medicine. Researchers in China first shared this idea in March 2020, and the findings were echoed by a paper out of Columbia University a month later. Latest research and advice on side effects and allergic reactions related to COVID-19 vaccines. Source Reference: Anderson JL, et al "Association of Sociodemographic Factors and Blood Group Type With Risk of COVID-19 in a US Population" JAMA Netw Open 2021; DOI: 10.1001/jamanetworkopen.2021.7429. CNN . Immune responses to the heterologous vaccination schedule were within the range of those reported using homologous schedules. Immunol. Neutralizing antibody levels usually increase after the second administration of mixed vaccines (22, 23). And for more signs you could've contracted the virus, check out If You Have This Symptom, There's an 80 Percent Chance You Have COVID. Interestingly, individuals with blood type A produced lower amounts of IFN- at 180240 days after vaccination and had lower neutralizing antibodies at 114 days than those with blood type B. This unusual clotting may cause different complications, including organ damage, heart attack and stroke. The mixed model distribution curves of log2-transformed neutralizing antibodies and log10-transformed cellular response with duration adjusted by age, sex, BMI, occupation, vaccination mode, duration since the second dose, interval between doses of vaccination, and ABO blood type were plotted using Prism 8.0 (GraphPad Software Inc., USA). Blood type, the researchers found, stood out as a potential key difference between the two groups. Wheatley AK, Juno JA, Wang JJ, Selva KJ, Reynaldi A, Tan HX, et al. Although the statistical analysis controlled for potential confounders, we included variables that showed significant associations with humoral and cellular responses in the mixed model. Experts say more . (D) Kinetics of B-lymphocyte count according to age. if( navigator.sendBeacon ) { Acute disseminated encephalomyelitis following the COVID-19 vaccine Ad26.COV2.S, a case report. This content includes information from experts in their field and is fact-checked to ensure accuracy. Progress and challenge of COVID-19 vaccine development. NJ, BW, QiZ, and JZ analyzed the immune data of the participants. The results were notable: Adjusting for demographics and co-morbidities, the risk for a COVID-19 diagnosis was 12 percent lower for people with type O blood and the risk for severe COVID-19 or death was 13 percent lower, compared to those with A, AB, or B blood types. The clots can clog up important . The worst outcome of these side effects is associated with VST, why it should not be missed and treated appropriately in due time. Unfortunately, to date, occupation- and blood type-disaggregated data on cellular and humoral immunogenicity have not been reported by studies on COVID-19 vaccines. An independent data-monitoring committee, comprising independent scientists not involved in this study, has been reviewing the data regularly for safety and scientific integrity. doi:10.1016/S1473-3099(21)00680-0, 27. It also can be potentially quite large and thus a bit unsettling. Whether mild or severe, data from the U.S. Centers for Disease Control and Prevention (CDC), has shown that women are bearing the brunt of vaccine reactions, and experts believe it may be due to . A review of neurological side effects of COVID-19 vaccination. -. This site needs JavaScript to work properly. The Public Health Agency of Canada, Health Canada, and provincial and territorial health authorities continue to: A higher IL-6 level was associated with older age, mixed-manufacturer vaccinations, intervals of less than 40 days between two doses of vaccination, and medical staff. Table2 Factors associated with the neutralization antibody concentration after the administration of the Chinese inactivated COVID-19 vaccine. In contrast, people with blood type O appear to have about a 50 percent reduced risk of severe COVID-19. Parameters of cell immune responses were evaluated by quantifying the levels of interferon (IFN)-, interleukin (IL)-6, and CD4, and counts of B-lymphocyte subsets in the plasma after overnight stimulation of whole blood with 2 g/mL SARS-CoV-2 spike peptides (Wuhan Huamei Biotechnology Ltd., Co., Wuhan, China) or dimethyl sulfoxide in whole-blood culture as a control, requiring only 2 mL blood (14). But recently, the genetics company 23andMe revealed preliminary data from their own study showing that a person's blood type, which is determined by the ABO gene, appears to affect susceptibility to coronavirus. Cytokine levels and lymphocyte subset counts were measured using flow cytometry (Beamcyte-1026; Changzhou Beamdiag Co., Ltd., Changzhou, China). doi:10.1016/S0140-6736(22)00770-X, 26. It shows the vaccine is teaching your body's immune system how to protect itself from the disease. The full coverage rate of the COVID-19 vaccination program has reached approximately 90% of the population required to be vaccinated in 2022 (10). The researchers at St. Michael's Hospital in Toronto, Canada, examined the test results of 225,556 Canadians who had been tested for COVID-19 between Jan. 15 and Jun. You've read a lot about what puts you at an increased risk of having a severe case of COVID-19, from smoking to carrying around extra weight to being over a certain age. These quick trivia tidbits will help you kill your boredom and impress your friends. Eur J Med Res. dvelopper et amliorer nos produits et services. A retrospective analysis of clinically confirmed long post-COVID vaccination syndrome. These include anaphylaxis, a severe reaction . Further inquiries can be directed to the corresponding author. Yin F, Wu Z, Xia X, Ji M, Wang Y, Hu Z. The two tubes with the EDTA anticoagulant were used to determine lymphocyte subsets with or without antigen-stimulated SARS-CoV-2 spike peptides, and the two tubes without the EDTA anticoagulant were used to determine neutralizing antibodies against SARS-CoV-2 and cytokines with or without antigen-stimulated SARS-CoV-2 spike peptides. We excluded 14 (2.4%) participants from the regression analysis and mixed model analysis due to missing data: 8 who withdrew their consent, 2 who did not answer age-related questions, 2 who missed a follow-up visit, and 2 who did not provide blood samples (Figure1). Exacerbating GuillainBarr syndrome eight days after vectorbased COVID19 vaccination. What Your Blood Type Has to Do With Getting Covid, This Coffee Shop Provides Free Therapy for Men, Your Privacy Choices: Opt Out of Sale/Targeted Ads. Unfolding the determinants of COVID-19 vaccine acceptance in China. doi: 10.1016/S2213-2600(21)00220-4, 19. Safety definitions and a list of solicited adverse events were defined as previously described (16, 17). Pain at the injection site, alongside redness and/or swelling Extended fatigue Headaches Widespread muscle pain Joint pain Chills Fever Nausea and vomiting According to current FDA publications,. A new large-scale study published in the journal Annals of Internal Medicinefound that your risk of catching COVID-19 is slashed if you have a particular blood type. Diarrhea. (AC) Kinetics of interferon-gamma levels according to (A) age, (B) blood type, and (C) occupation. Blood clots with low platelets Capillary leak syndrome Guillain-Barr syndrome (GBS) Ongoing monitoring of side effects and reactions As the COVID-19 vaccine rollout continues across Canada, safety monitoring is ongoing. We may earn commission from links on this page, but we only recommend products we back. BM and JZ collected data and YL reviewed the manuscript. } else { If youre type O, you naturally make antibodies against Type A and Type B, Dr. Udden says. Before The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Therefore, we designed a multicenter, longitudinal, observational study to evaluate the immunogenicity and reactogenicity of a second dose of inactivated vaccine among those who received the two vaccines from different manufacturers. Pour en savoir plus sur la faon dont nous utilisons vos donnes personnelles, veuillez consulter notre politique relative la vie prive et notre politique en matire de cookies. Epub 2021 Oct 31. J Neuroimmunol. Results: Most participants [582/595; 146 male participants, 449 female participants; mean age 35 (2650 years)] rapidly developed neutralizing antibodies after two doses of the vaccine administered 3-weeks apart. It is suggested that pain in the application area is the most frequent side effect among workers in a Mexican hospital who received the Pfizer BioNTech vaccine against COVID-19. and transmitted securely. This study was a multicenter, longitudinal, prospective, observational study conducted in two hospitals (Henan Provincial Peoples Hospital and Zhengzhou Municipal Chinese Medicine Hospital) and one institution (Henan Electric Power Survey and Design Institute) in central China. Follow. Are the Vaccines Safe? Expert Rev Vaccines (2021) 20:13617. Ackah BBB, Woo M, Stallwood L, Fazal ZA, Okpani A, Ukah UV, et al. Future Sci OA (2021) 7:FSO735. The question of a possible relationship between blood type and disease risk has been a topic of active research since early in the pandemic. The most frequent neurological side effects of SARS-CoV-2 vaccines are headache, Guillain-Barre syndrome (GBS), venous sinus thrombosis (VST), and transverse myelitis.

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